correlational
Analysis v1
Strong Support
When rats were given a drug to raise their uric acid levels, their blood pressure went up and their blood vessels didn’t relax as well when insulin was present — this suggests high uric acid might hurt blood vessel function and raise blood pressure in animals.
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0
Evidence from Studies
Supporting (1)
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Community contributions welcome
8
Uric acid induces endothelial dysfunction by vascular insulin resistance associated with the impairment of nitric oxide synthesis
Cross-Sectional Study
Animal
2014 JulThe study gave rats a substance that raises uric acid, and their blood pressure went up and blood vessels didn’t relax as well — just like the claim says.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.