mechanistic
Analysis v1
Strong Support
Scientists think that two proteins, Filamin-C and BAG3, might act like a sensor in muscle cells that detects when the muscle is being stretched or worked hard, and then turns on or off other signals that help the muscle grow — but they’re not sure exactly how this works yet.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Stimuli and sensors that initiate skeletal muscle hypertrophy following resistance exercise.
Narrative Review
2019 Jan 1The study says that when you lift weights, your muscles sense the pull through a system involving filamin-C and BAG3 proteins, which help control growth signals — and while scientists don’t fully understand it yet, this system is a strong candidate for how muscles grow from exercise.
Contradicting (0)
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No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.