mechanistic
Analysis v1
Strong Support
Fibrates are pills that lower bad cholesterol, but they seem to protect your heart even more than just lowering cholesterol should — so they might be doing something extra to keep your heart healthy.
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0
Evidence from Studies
Supporting (1)
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Community contributions welcome
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Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis.
Systematic Review With Meta-Analysis
Human
2016 Sep 27This study found that fibrates lowered heart disease risk more than expected just from how much they lowered 'bad' cholesterol, meaning they probably help the heart in other ways too.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.