correlational
Analysis v1
Strong Support
Drugs designed to lower 'bad' cholesterol (LDL) by blocking CETP didn't protect people's hearts as much as scientists thought they would—so maybe these drugs have hidden side effects, or lowering LDL alone isn't enough to prevent heart problems.
52
0
Evidence from Studies
Supporting (1)
52
Community contributions welcome
52
Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis.
Systematic Review With Meta-Analysis
Human
2016 Sep 27This study found that drugs meant to lower 'bad' cholesterol (CETP inhibitors) didn’t reduce heart problems as much as you’d expect just from how much they lowered cholesterol, which means they might have other problems or just don’t help as much as hoped.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.