When middle-aged women lift weights or do strength training, their body produces less of two inflammation-related signals (CCL28 and CXCL4), and this seems to go hand-in-hand with their skin making more of a helpful protein called biglycan—which might mean these signals normally slow down skin repair.

Evidence from Studies

Supporting (0)

0

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No supporting evidence found

Contradicting (1)

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48

Resistance training rejuvenates aging skin by reducing circulating inflammatory factors and enhancing dermal extracellular matrices

Randomized Controlled Trial

Human

2023 Jun 23

The study found that weight training made skin thicker and increased a protein called biglycan, but it never checked if it lowered the two specific inflammatory chemicals mentioned in the claim, so we can't say the full claim is true.

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Resistance training rejuvenates aging skin by reducing circulating inflammatory factors and enhancing dermal extracellular matrices

Score: 48

DOI: 10.1038/s41598-023-37207-9

Similar Assertions

Working out with weights can lower certain inflammatory chemicals in the blood of middle-aged women, and those chemicals normally make a skin protein called biglycan — so when they drop, biglycan drops too, which might help slow down skin aging.

0

48

91%

If middle-aged women lift weights, it lowers certain body chemicals that cause inflammation, but if they do cardio like walking or cycling, it lowers different inflammation chemicals instead—so the kind of exercise you do changes which inflammation signals go down.

0

48

72%