Sunlight's UV rays might mess up your skin's internal clock at night, making it harder for your skin to heal, fight damage, and calm inflammation while you sleep.

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The Melatonin–Mitochondrial Axis: Engaging the Repercussions of Ultraviolet Radiation Photoaging on the Skin’s Circadian Rhythm

Narrative Review

2023 Apr 26

The study talks about how sunlight affects the skin’s daily rhythm and mentions protection from damage, but it doesn’t prove that UV light turns off specific body-clock genes in skin cells as claimed.

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

The Melatonin–Mitochondrial Axis: Engaging the Repercussions of Ultraviolet Radiation Photoaging on the Skin’s Circadian Rhythm

Score: 1

DOI: 10.3390/antiox12051000

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