Back to Study: Glycine ingestion improves subjective sleep qualit...
causal
positive effect

Taking 3 grams of glycine before bed makes people who have trouble sleeping feel more satisfied with their sleep.

Scientific Claim

A single 3g dose of glycine taken before bedtime significantly improves subjective sleep satisfaction in adults with chronic poor sleep, as measured by the St. Mary's Hospital Sleep Questionnaire (P=0.046).

Source Excerpt

Significant beneficial effects of glycine were revealed in Question 11 'How satisfied were you with last night's sleep?' (P=0.046, Fig. 1)

Evidence from Studies

Supporting Studies

Glycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changes

Crossover Trial
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30%
Evidence Assessment
Supported

This was a randomized single-blinded crossover trial with 11 participants showing statistically significant improvement in sleep satisfaction (P=0.046) after glycine ingestion compared to placebo. The study design allows for causal inference despite small sample size.