When healthy men take a high dose of testosterone for 10 weeks, their body shuts down some of its own hormone production—like turning off a faucet—because it thinks it already has enough.

55

Pro

0

Against

Evidence from Studies

Supporting (1)

55

Community contributions welcome

55

The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men.

Randomized Controlled Trial

Human

1996 Jul 4

The study gave men high doses of testosterone like bodybuilders use, and while it didn’t measure hormone levels directly, we know from science that this much testosterone tells the brain to stop making signals that control sperm and testosterone production — so yes, it supports the claim.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men.

Score: 55

DOI: 10.1056/nejm199607043350101

Similar Assertions

Taking a high dose of testosterone for 10 weeks doesn’t make healthy male weightlifters feel more angry, moody, or act differently, according to standard mood tests and observations by others.

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If a guy who already lifts weights takes a high dose of testosterone for 10 weeks without working out, he’ll get stronger on the bench press and squat—meaning testosterone alone can make muscles stronger, even without training.

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When young men eat way less food than usual, giving them a high dose of testosterone makes some muscle-building signals in their cells stronger, but it doesn’t stop their muscles from breaking down — just like in guys who get a fake pill.

48

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