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Strong Support

Taking berberine pills daily for a few months may help lower your bad cholesterol and overall cholesterol levels if you have high cholesterol, diabetes, or metabolic syndrome.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Update on the Benefits and Mechanisms of Action of the Bioactive Vegetal Alkaloid Berberine on Lipid Metabolism and Homeostasis

Narrative Review
Human
2018

This study doesn’t do a new experiment, but it looks at lots of other studies and says berberine pills really do lower bad cholesterol in people with high cholesterol or diabetes — just like the claim says.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Update on the Benefits and Mechanisms of Action of the Bioactive Vegetal Alkaloid Berberine on Lipid Metabolism and Homeostasis

Score: 1
DOI: 10.1155/2018/7173920

Similar Assertions

Taking berberine pills for 3 months helped people with high cholesterol lower their bad fats in the blood—cholesterol dropped by almost a third, and triglycerides by over a third—so it might be a natural way to help manage cholesterol.

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94%

Taking berberine pills every day for 3 months can lower your bad cholesterol and fat levels in the blood by a lot—like cutting your cholesterol by nearly a third.

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93%

When hamsters ate a fatty, cholesterol-rich diet and were given a daily pill of berberine for 10 days, their bad cholesterol levels dropped a lot—like going from really high to much healthier levels.

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87%

Taking berberine pills may help lower your 'bad' cholesterol and fat in your blood by about 10–20%, which could be good for your heart.

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86%

Taking a natural supplement called berberine hydrochloride twice a day for three months helped people with high bad cholesterol lower it by about 25%, without changing their good cholesterol levels.

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86%