Vitamin D can change the daily rhythm of key genes in skin cells, according to lab studies.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Differential Regulation of Circadian Clock Genes by UV-B Radiation and 1,25-Dihydroxyvitamin D: A Pilot Study during Different Stages of Skin Photocarcinogenesis

Cross-Sectional Study

In Vitro

2024 Jan 14

The study shows that active vitamin D changes the timing of one clock gene (BMAL1) and reduces another (PER2) in skin cells, just like the claim says.

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Differential Regulation of Circadian Clock Genes by UV-B Radiation and 1,25-Dihydroxyvitamin D: A Pilot Study during Different Stages of Skin Photocarcinogenesis

Score: 7

DOI: 10.3390/nu16020254

Similar Assertions

UV-B light and vitamin D affect our skin cells' internal clocks in totally different ways — and vitamin D doesn’t explain how UV-B changes those clocks.

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UV-B light at a certain dose changes how a key body-clock gene behaves in skin cells, suggesting sunlight might reset the skin’s internal clock all on its own.

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72%

Getting the right amount of sunlight helps your body make vitamin D and keeps your sleep-wake cycle on track, which together help keep you healthy.

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70%