quantitative
Analysis v1
5
0
The amount of LDH released by cells in the gel model goes down at first, then up, showing changes in cell damage over three weeks.
Scientific Claim
Lactate dehydrogenase release in a co-cultured hydrogel model decreases initially and then increases, indicating fluctuating cytotoxicity levels over 21 days.
Original Statement
“LDH release decreased on day 7 and increased on day 14 to remain stable on day 21 (Figure 12).”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
definitive
Can make definitive causal claims
Assessment Explanation
The study directly measured LDH release, so the trend described is a factual observation.
Evidence from Studies
Supporting (1)
5
5
Triphasic 3D In Vitro Model of Bone-Tendon-Muscle Interfaces to Study Their Regeneration
Cross-Sectional Study
In Vitro
2023 Jan 13Contradicting (0)
0
No contradicting evidence found