correlational
Analysis v1
Strong Opposition
The more fat and cholesterol packed inside a person’s artery plaque, the more the immune cells inside it are dividing — suggesting the fat itself is fueling their growth.
0
61
Evidence from Studies
Supporting (0)
0
Community contributions welcome
No supporting evidence found
Contradicting (1)
61
Community contributions welcome
61
Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering
Cohort Study
Human
2020 Dec 9When fat levels in artery plaques go down, the immune cells (macrophages) stop multiplying as much — so more fat doesn’t make them multiply more, it’s the opposite.
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.