mechanistic
Analysis v1
Strong Support
Swapping saturated fats like butter for unsaturated fats like olive oil doesn’t seem to help your body remove cholesterol better or change a key protein linked to cholesterol levels — so those things probably aren’t why this diet change helps lower bad cholesterol.
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0
Evidence from Studies
Supporting (1)
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Community contributions welcome
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Replacing Saturated Fats with Unsaturated Fats from Walnuts or Vegetable Oils Lowers Atherogenic Lipoprotein Classes Without Increasing Lipoprotein(a)
Randomized Controlled Trial
Human
2020 Apr 1The study found that swapping saturated fats for unsaturated fats improved cholesterol levels, but didn’t change how the body removes cholesterol or a protein called PCSK9, meaning those aren’t the reasons for the benefit.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.