correlational
Analysis v1
Strong Support

When there’s too much phosphate in the body, it might cause kidney cells to make more of a protein called PAI-1, and this protein could be one reason why kidney tissue gets scarred or ages faster in animals.

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Pro
0
Against

Evidence from Studies

Supporting (1)

1

Community contributions welcome

This study shows that too much phosphate in the body makes a protein called PAI-1 go up, and that protein causes cells to age faster and scar tissue to form — which is exactly what the claim says.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.