descriptive
Analysis v1
Strong Opposition
Using tretinoin cream on sun-damaged skin doesn’t always make it feel smoother to the touch, even after two years of use—so it might work better for reducing wrinkles or dark spots than for smoothing rough skin texture.
0
24
Evidence from Studies
Supporting (0)
0
Community contributions welcome
No supporting evidence found
Contradicting (1)
24
Community contributions welcome
24
Topical tretinoin for treating photoaging: A systematic review of randomized controlled trials
Systematic Review
Human
2022 MarThe study found that tretinoin cream consistently improved many signs of sun-damaged skin, including wrinkles and discoloration, over two years. The claim says it doesn’t work well for rough skin texture, but the study’s results suggest it likely does, so the claim is wrong.
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.