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Back to Study: Comparing the effects of ipragliflozin versus metf...
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Analysis v1
Strong Support

When Japanese adults with type 2 diabetes take sitagliptin plus ipragliflozin for 24 weeks, their outer fat layer shrinks, but those taking metformin gain outer fat, with a clear difference between the two treatments.

72
Pro
0
Against

Evidence from Studies

Supporting (1)

72

Community contributions welcome

72

Comparing the effects of ipragliflozin versus metformin on visceral fat reduction and metabolic dysfunction in Japanese patients with type 2 diabetes treated with sitagliptin: A prospective, multicentre, open‐label, blinded‐endpoint, randomized controlled study (PRIME‐V study)

Randomized Controlled Trial
Human
2019 Aug

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No contradicting evidence found

Source Study

Comparing the effects of ipragliflozin versus metformin on visceral fat reduction and metabolic dysfunction in Japanese patients with type 2 diabetes treated with sitagliptin: A prospective, multicentre, open‐label, blinded‐endpoint, randomized controlled study (PRIME‐V study)

Score: 72
DOI: 10.1111/dom.13750

Similar Assertions

For Japanese adults with type 2 diabetes taking sitagliptin, taking ipragliflozin for 24 weeks makes belly fat inside the body decrease more than taking metformin, with a noticeable difference in fat loss.

72
0
96%

For Japanese adults with type 2 diabetes on sitagliptin, ipragliflozin lowers insulin levels significantly more than metformin, which actually slightly raises insulin levels, with a clear difference between the two treatments.

72
0
93%

For Japanese adults with type 2 diabetes on sitagliptin, metformin reduces bad cholesterol more than ipragliflozin, which actually raises bad cholesterol levels, with a clear difference between the two treatments.

72
0
87%

For Japanese adults with type 2 diabetes on sitagliptin, ipragliflozin reduces waist size more than metformin after 24 weeks, with a noticeable difference in how much waist circumference decreases.

72
0
87%

For Japanese adults with type 2 diabetes on sitagliptin, ipragliflozin boosts good cholesterol more than metformin after 24 weeks, with a noticeable difference in how much HDL levels rise.

72
0
86%