When mice had more taurocholic acid in their blood, their fat cells turned on more genes that help break down fat.

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A moderate lard-included diet reduces fat deposition and inflammation in the adipose tissue

Cohort Study

Animal

2025 Dec 12

The study found that when mice ate a moderate amount of lard, their bodies made more of a substance called TCA, which helped their fat cells break down fat instead of storing it — exactly what the claim says.

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Source Study

A moderate lard-included diet reduces fat deposition and inflammation in the adipose tissue

Score: 6

DOI: 10.1038/s41538-025-00657-8

Similar Assertions

In lab-grown fat cells and immune cells, adding taurocholic acid made the fat cells store less fat and turned immune cells into a type that reduces inflammation.

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Mice that ate lard had more of a bile acid called TCA in their blood, and the more TCA they had, the smaller their fat cells and the more their bodies were breaking down fat and calming inflammation.

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When scientists added TCA (a bile acid) to fat cells and immune cells in a dish, it made the fat cells store less fat and the immune cells become less inflamed, mimicking what was seen in mice that ate lard.

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Mice that ate a moderate amount of lard had more of a substance called taurocholic acid in their blood than mice that ate other oils.

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