mechanistic
Analysis v1
Strong Support
If overweight women who’ve gone through menopause eat 500 fewer calories a day for about 11 weeks, their bodies use and make less of a key protein building block called leucine—but they don’t lose more protein overall or burn more of it for energy.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Resistance Training Preserves Fat‐free Mass Without Impacting Changes in Protein Metabolism After Weight Loss in Older Women
Randomized Controlled Trial
Human
2009 JulThe study put overweight older women on a diet that cut 500 calories a day for 11 weeks and found their body used less of a key protein building block (leucine) for making and breaking down muscle, but didn’t change overall protein balance — just like the claim said.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.