When p70 S6 kinase gets phosphorylated in muscle, it leads to more phosphorylation of ribosomal protein S6, which helps make specific proteins from mRNA.
Scientific Claim
Phosphorylation of p70 S6 kinase and subsequent phosphorylation of ribosomal protein S6 is associated with enhanced translation of specific mRNAs in human muscle.
Source Excerpt
“Activation of p70 S6 kinase, and subsequent phosphorylation of the ribosomal protein S6, is associated with enhanced translation of specific mRNAs.”
Evidence from Studies
Supporting Studies
Branched-chain amino acids activate key enzymes in protein synthesis after physical exercise.
The study states that phosphorylation of p70 S6 kinase and ribosomal protein S6 is associated with enhanced translation of specific mRNAs. This is a descriptive finding about the relationship between these phosphorylation events and protein synthesis.
⚠️ Overstated
The study design is unclear (Level 5 evidence), and the claim uses 'is associated with' which is appropriate, but the phrase 'enhanced translation' implies causation. The study only shows association between phosphorylation and translation.
More accurate phrasing:
“Phosphorylation of p70 S6 kinase and subsequent phosphorylation of ribosomal protein S6 is associated with enhanced translation of specific mRNAs in human muscle.”