When people eat a low-fat, high-carb diet, their body burns less fat for energy overall, which might help explain why fat builds up in the blood.

After eating, people on a low-fat, high-carb diet have higher levels of fat, sugar, and insulin in their blood for longer than when they eat a diet with more fat, which might stress the body over time.

If you're overweight and eat fewer carbs instead of less fat for four weeks, you might lose more body fat—even if you lose the same amount of total weight as someone on a low-fat diet.

Eating fewer carbs and calories helps overweight people lose weight by improving how their bodies process energy. This finding is from the abstract summary - full study details were not available

Eating a diet low in fat and high in carbs makes the body less able to clear fat from the blood, causing triglyceride levels to rise sharply.