In untrained young adults, performing seated calf raises with the knee bent for 12 weeks leads to less than 1.7% increase in gastrocnemius muscle size, indicating that training biarticular muscles at...
Mechanism
Synthesis from 1 study
The gastrocnemius muscle grows only when it is stretched while pushing against resistance. When the knee is bent during calf raises, the muscle is already short and cannot generate enough internal tension to trigger growth. When the knee is straight, the muscle stretches as it contracts, creating...
Most probable mechanism
When a muscle is stretched while it contracts, it pulls harder on its fibers and creates more internal stress, which signals the muscle to grow. When the muscle is not stretched during contraction, this signal is weak and the muscle barely grows.
Knee extension during plantarflexion places the gastrocnemius at a longer muscle length, increasing passive tension and sarcomere strain
Increased sarcomere strain activates mechanotransduction pathways including integrin, FAK, and mTOR signaling in muscle fibers
Lengthened contractions elevate metabolic stress through localized hypoxia and lactate accumulation, increasing cellular energy demand
Mechanical tension and metabolic stress together upregulate anabolic signaling and satellite cell activity, enhancing muscle protein synthesis
Net muscle protein synthesis exceeds breakdown, resulting in increased muscle volume specifically in the gastrocnemius
Evidence from Studies
Supporting (1)
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Triceps surae muscle hypertrophy is greater after standing versus seated calf-raise training
Contradicting (0)
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Gold Standard Evidence Needed
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