When scientists turned on a specific type of brain receptor in the hunger center of fasted rats, the rats ate more food—and when they turned it off, the rats ate less.

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Role of ventromedial hypothalamic dopaminergic D1-like receptors in regulating standard food intake in 24-hour food-deprived male rats.

Cohort Study

Animal

2025 Sep 15

When scientists turned on a specific brain receptor in hungry rats, the rats ate more—and they ate even more with higher doses. When they blocked that same receptor, the rats stopped eating more, proving the receptor controls how much they eat.

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No contradicting evidence found

Source Study

Role of ventromedial hypothalamic dopaminergic D1-like receptors in regulating standard food intake in 24-hour food-deprived male rats.

Score: 6

DOI: 10.1016/j.brainres.2025.149846

Similar Assertions

A certain type of brain chemical signal in the hunger center of fasted rats helps tell them to eat more.

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The rats ate more because of the brain receptor change—not because they were moving around more or less.

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A part of the rat brain called the ventromedial hypothalamus helps control eating when the rat is hungry, and dopamine signals through D1 receptors are part of how it works.

91%