If an adult has low 'good' cholesterol plus high 'bad' cholesterol and high triglycerides, their risk of heart disease is much higher than if they just had low 'good' cholesterol alone.

If someone has high 'good' cholesterol but also high 'bad' cholesterol and triglycerides, it doesn’t seem to protect their heart anymore — it’s like the good stuff loses its power when the bad stuff is too high.

If you're an adult with high 'good' cholesterol (HDL), especially when your 'bad' cholesterol and triglycerides are low, you're about 40% less likely to have heart disease compared to people with low good cholesterol — it seems high good cholesterol helps protect your heart when the rest of your lipid profile is healthy.

If an adult has both low 'good' cholesterol and high triglycerides, their heart disease risk goes up more than if they just had low good cholesterol — it's like the high triglycerides make the low good cholesterol risk worse.

If you're a healthy adult and only your 'good' cholesterol is low—but your 'bad' cholesterol and triglycerides are already low—this might not actually raise your heart disease risk much.

If an adult has both low 'good' cholesterol and high 'bad' cholesterol, their risk of heart disease is higher than if they only had low 'good' cholesterol.