causal
Analysis v1
Strong Support
When sunscreen chemicals like avobenzone are trapped inside a special ring-shaped molecule called β-cyclodextrin, they don’t soak into the skin as much as when they’re just mixed in — and this works better in a creamy lotion base using rat skin in a lab test.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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The Effect of Beta-Cyclodextrin on Percutaneous Absorption of Commonly Used Eusolex® Sunscreens
Cohort Study
Animal
2013 NovScientists found that when sunscreens were mixed with β-cyclodextrin in a special way (complexation), they stayed on the skin’s surface better and didn’t soak in as much as when just stirred in (physical mixture), which is exactly what the claim says.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.