mechanistic
Analysis v1
Strong Support
If your gut gets too 'leaky,' stuff that should stay in your intestines can get into your bloodstream and possibly set off your immune system in a way that leads to autoimmune diseases like Crohn’s or rheumatoid arthritis.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
1
Increased Intestinal Permeability: An Avenue for the Development of Autoimmune Disease?
Narrative Review
Animal
The study explains that when the gut barrier gets leaky, harmful substances can escape into the body and trigger autoimmune diseases like Crohn’s and rheumatoid arthritis, which supports the claim.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.