causal
Analysis v1
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0
Whether obese women eat a low-fat or high-fat diet while cutting calories, their fat tissue genes respond the same way, so the type of fat in the diet doesn't change how these genes work during weight loss.
Scientific Claim
Macronutrient composition (low-fat vs high-fat) does not differentially affect adipose tissue gene expression during weight loss in obese women.
Original Statement
“none of the genes showed a significantly different response to the diets.”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
definitive
Can make definitive causal claims
Assessment Explanation
The RCT design establishes causation for the lack of differential effect between diets on gene expression. The verb 'does not differentially affect' is appropriate for this causal claim.
Evidence from Studies
Supporting (1)
55
55
Adipose tissue gene expression in obese subjects during low-fat and high-fat hypocaloric diets
Randomized Controlled Trial
Human
2005 JanContradicting (0)
0
No contradicting evidence found