In people who regularly lift weights, training the elbow flexors with either a limited or full range of motion for 8 weeks leads to similar increases in muscle size, as measured at specific points...
Mechanism
Synthesis from 1 study
Whether you lift halfway or all the way, if you keep your biceps stretched under weight, it pulls on the muscle fibers just enough to turn on their growth signal. This makes the muscle thicker, especially in the part that stretches the most — so both methods work equally well for building size.
Most probable mechanism
When muscles are stretched under load for a long time during exercise, the fibers feel more pull, which turns on a cellular signal that tells the muscle to build more protein, making it thicker — especially in the part of the muscle that's stretched the most.
The elbow flexor muscles are held in a lengthened position throughout the concentric and eccentric phases of movement, maintaining high passive tension in the sarcomeres and extracellular matrix.
Elevated mechanical tension from sustained stretch activates the mTORC1 signaling pathway, which increases ribosomal biogenesis and enhances the rate of muscle protein synthesis.
Increased protein synthesis leads to net accretion of contractile proteins, particularly in the distal regions of the muscle where mechanical strain is greatest due to greater strain gradients near the tendon insertion.
Regional accumulation of new contractile material increases the cross-sectional area of muscle fascicles, resulting in measurable thickening at 50% and 70% humeral length.
Evidence from Studies
Supporting (1)
Community contributions welcome
Contradicting (0)
Community contributions welcome
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.