When healthy adults aged 18–80 consume 30 grams of protein from a plant-based drink or an animal-based solid meal, the reduction in subjective feelings of hunger is the same, even though one is a...
Mechanism
Synthesis from 1 study
The body releases the same fullness signals when you drink or eat 30 grams of protein, no matter if it comes from plants or animals. The amino acids from the protein trigger hormone release in the lower gut, which tells the brain to stop feeling hungry, and this process works the same whether the...
Most probable mechanism
When a person consumes 30 grams of protein, whether in a drink or a solid meal, the amino acids from the protein reach the lower intestine and trigger cells there to release hormones that signal the brain to reduce hunger. These hormones slow down digestion and make the person feel full, so they eat less later, no matter if the protein came from plants or animals or was drunk or eaten.
Amino acids from digested dietary protein reach the distal small intestine and colon
Amino acids activate G-protein-coupled receptors on enteroendocrine L-cells in the intestinal lining
L-cell activation triggers intracellular calcium signaling and exocytosis of glucagon-like peptide-1 and peptide YY into the bloodstream
Circulating glucagon-like peptide-1 and peptide YY bind to receptors on vagal afferent nerves and neurons in the hypothalamus
Neural and hormonal signals reduce activity in hunger centers and increase activity in satiety centers of the brain, suppressing subjective appetite
Evidence from Studies
Supporting (1)
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