Your body’s inflammation response to hard eccentric exercise fades quickly after the first time—you don’t stay inflamed if you keep doing it.
Scientific Claim
C-reactive protein levels, a marker of systemic inflammation, do not show sustained elevation following repeated eccentric exercise sessions in untrained men, suggesting that inflammation is transient and adapts with training.
Original Statement
“Biochemical markers of muscle damage (creatine kinase) and inflammation (C-reactive protein) were measured prior and 2 days post each session.”
Evidence Quality Assessment
Claim Status
understated
Study Design Support
Design supports claim
Appropriate Language Strength
probability
Can suggest probability/likelihood
Assessment Explanation
The abstract mentions CRP measurement but does not report results; the claim infers adaptation from the overall conclusion. This requires inference beyond explicit data.
More Accurate Statement
“C-reactive protein levels following eccentric exercise are likely to show transient elevation after the first bout but no sustained elevation after repeated sessions in untrained men, suggesting adaptation of the inflammatory response.”
Evidence from Studies
Supporting (1)
Eccentric exercise per se does not affect muscle damage biomarkers: early and late phase adaptations
When untrained men first did intense eccentric exercises, their bodies showed signs of inflammation, but after doing it weekly for 10 weeks, their bodies got used to it and stopped reacting — so inflammation didn’t stick around.