mechanistic
Analysis v1
Strong Support
Doing weight training either heavy or light until you can't do another rep for nine weeks doesn't change your hormone levels in your saliva, and that's okay—your muscles can still get stronger and bigger even if your hormones don't budge.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Muscle Hypertrophy, Strength, and Salivary Hormone Changes Following 9 Weeks of High- or Low-Load Resistance Training
Randomized Controlled Trial
Human
2025 Dec 30The study had guys lift heavy or light weights to exhaustion for nine weeks and found their hormone levels didn’t change much — yet their muscles still got bigger and stronger. So, you don’t need big hormone spikes to grow muscle.
Contradicting (0)
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Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.