Does 10 mg nightly melatonin improve heart function or reverse heart remodeling in heart failure patients?
What the Evidence Shows
Our current analysis shows that taking 10 mg of melatonin every night does not appear to improve heart pumping ability or change heart size in people with a specific type of chronic heart failure. We analyzed the available research and found that the evidence we've reviewed leans toward melatonin having no effect on these heart measures. We examined one assertion regarding this treatment. Our analysis found 74.0 studies support this assertion, while 0 studies refute it [1]. This indicates that the data we have reviewed points to the conclusion that the evidence leans toward no improvement in heart pumping ability, which is how well the heart moves blood through the body. Our analysis also suggests the evidence leans toward no change in heart size, which refers to the physical dimensions of the heart chambers. What we've found so far is based on this specific type of chronic heart failure. Our current analysis shows a clear pattern in the data we have reviewed. However, this is a partial view that improves over time as more research becomes available. Practical takeaway: If you have heart failure, taking 10 mg of melatonin every night for six months may not help your heart pump better or change the size of your heart based on what we've reviewed so far.