Does evolocumab reduce LDL cholesterol in adults with diabetes?

Evolocumab & LDL1 min readUpdated June 7, 2026

What the Evidence Shows

We analyzed the available evidence on evolocumab and LDL cholesterol in adults with diabetes, and what we’ve found so far suggests it lowers LDL cholesterol significantly. In one study involving adults with diabetes who did not have advanced artery disease, evolocumab reduced LDL cholesterol by...

Evidence from Studies

Supporting (0)
No supporting evidence found
Contradicting (0)
No contradicting evidence found
Primary Studies (1)

Evolocumab to Reduce First Major Cardiovascular Events in Patients Without Known Significant Atherosclerosis and With Diabetes

DOI: 10.1001/jama.2026.3277

Update History

Published
June 7, 2026·Last updated June 7, 2026
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