Does sitagliptin improve insulin sensitivity and fasting glucose in obesity and prediabetes despite raising GLP-1 and GIP?

We analyzed two assertions about sitagliptin in people with obesity and prediabetes, and both point to the same pattern: sitagliptin raises gut hormones like GLP-1 and GIP, but does not improve insulin sensitivity or lower fasting glucose [1][2]. This is different from liraglutide, which directly...