What is the acceptable daily intake of ferrocyanide in food additives?
What the Evidence Shows
What we've found so far is that the acceptable daily intake of ferrocyanide in food additives may be up to 0.03 milligrams per kilogram of body weight [1]. This amount is based on our analysis of the available evidence, which includes findings derived from rat studies with a large safety margin added in [1].
Our current analysis shows that this level of intake has been considered safe in assessments we’ve reviewed. The evidence we’ve examined does not suggest harm at this level, but it’s important to note that the conclusion comes from a limited number of studies — specifically, those involving animal testing where effects on health were monitored and then adjusted to estimate a safe human exposure level .
The evidence we've reviewed leans toward this intake level being acceptable for daily consumption over a lifetime, assuming the safety buffer accounts for differences between animals and humans, as well as variations among individuals . However, we are basing this entirely on the one assertion available, and no studies in our current review refute or challenge this level.
We do not have enough evidence to say whether long-term intake near this level has any measurable effects in humans, nor do we have human clinical trials to confirm these findings directly. Our analysis remains limited by the lack of human data and the reliance on animal models.
As we continue to review new research, our understanding may change.
Practical takeaway: If you’re exposed to ferrocyanide through food additives, the amount considered acceptable in our current analysis is very small — about 0.03 mg per kilogram of your body weight each day — and includes a safety buffer.