Can stretching make muscles bigger even if you don’t squeeze them?

Original Title

Efficacy of passive repetitive stretching of skeletal muscle on myofiber hypertrophy and genetic suppression on MAFbx, MuRF1, and myostatin

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Summary

Scientists stretched mice legs without making the muscles work, just by moving the ankle. They did this many times a day for two weeks and then checked the muscles.

Proposed Mechanism

No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.

Quality Analysis
Methodology
7%
Lower QualityOverall Score
Cross-Sectional StudyBiology

Systematic Reviews & Meta-Analyses

Max 100

Randomized Controlled Trials

Max 90

Cohort Studies

Max 72

Case-Control Studies

Max 58

Cross-Sectional Studies

Max 44

Case Reports & Case Series

Max 30

Expert Opinion & Narrative Reviews

Max 5
StrongerWeaker
Cross-Sectional Studies
Level 3b
7

7 / 44

Evidence Score

A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.

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