How a heart chemical helps burn fat in fat cells
Atrial natriuretic peptide regulates lipid mobilization and oxygen consumption in human adipocytes by activating AMPK.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
A chemical from the heart called ANP tells fat cells to burn more fat and energy. It works by turning on a switch in the cell called AMPK.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
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A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
A chemical from the heart called ANP tells fat cells to burn more fat and energy. It works by turning on a switch in the cell called AMPK.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 534 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Publication
Authors
Souza SC, Chau MD, Yang Q, Gauthier MS, Clairmont KB, Wu Z, Gromada J, Dole WP
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Claims (5)
ANP helps break down fat in human fat cells in the lab, and it does this by turning on a specific switch called the alpha2 part of AMPK. If you block that switch, ANP can't do its fat-burning job anymore.
When your cells are running low on energy, a protein called AMPK senses this and tells the cell to break down stored sugar and fat to make more fuel.
A hormone called ANP might supercharge fat cells in a lab, making them burn fat seven times more and use twice as much oxygen by turning on a specific energy sensor in the cell.
A hormone called ANP might help fat cells burn more energy by boosting their tiny power plants, according to lab studies.
A hormone called ANP might help fix broken energy factories in fat cells that aren't responding well to insulin — at least in lab dishes.