A long-lasting diabetes medicine helper
A novel exendin-4 human serum albumin fusion protein, E2HSA, with an extended half-life and good glucoregulatory effect in healthy rhesus monkeys.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists made a new medicine called E2HSA by combining a diabetes drug part with a blood protein to make it last longer in the body. They tested it in labs and monkeys.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 56 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists made a new medicine called E2HSA by combining a diabetes drug part with a blood protein to make it last longer in the body. They tested it in labs and monkeys.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 56 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Publication
Authors
Zhang L, Wang L, Meng Z, Gan H, Gu R, Wu Z, Gao L, Zhu X, Sun W, Li J, Zheng Y, Dou G
Related Content
Claims (6)
A new diabetes drug version lasts much longer in the body—about two and a half days—compared to the original, so you might only need to take it once a week instead of every day.
A modified compound called E2HSA still works in lab tests like a diabetes drug, even if it's not as strong as the original version.
In healthy monkeys, a substance called E2HSA seems to help control blood sugar after meals and during fasting, which means it might help regulate blood sugar overall.
This drug called E2HSA seems to make monkeys eat less the more they get, which might help control their appetite and improve their metabolism.
In monkeys, a substance called E2HSA helped their bodies release more insulin when blood sugar went up and kept sugar levels more stable during tough metabolic tests.