Can you swallow joint stuff and get it in your joints?
Absorption, uptake and tissue affinity of high-molecular-weight hyaluronan after oral administration in rats and dogs.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists gave rats and dogs a special goo (hyaluronan) to eat and tracked where it went using a harmless glow.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 59 / 72
Evidence Score
Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists gave rats and dogs a special goo (hyaluronan) to eat and tracked where it went using a harmless glow.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 59 / 72
Evidence Score
Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.
Publication
Authors
Balogh L, Polyak A, Mathe D, Kiraly R, Thuroczy J, Terez M, Janoki G, Ting Y, Bucci LR, Schauss AG
Related Content
Claims (5)
When rats swallow a special kind of big molecule labeled with a traceable marker, most of it comes out in their poop within two days — like 9 out of 10 pieces or more.
When you give a big sugar-like molecule called hyaluronan to rats and dogs by mouth, it spreads through their bodies in a different way than a radioactive substance called technetium pertechnetate does.
When someone swallows a substance called technetium pertechnetate, it quickly leaves the body through urine and tends to collect in certain parts like the thyroid, stomach, kidneys, and bladder.
When rats and dogs swallow a big molecule called hyaluronan, their bodies absorb it and it shows up in places like their joints, spine, and saliva glands—and it stays there for almost two days.
When rats and dogs swallow a special kind of slippery molecule labeled with a tracking dye, the dye shows up in their skin, bones, and joints a day later—but a different tracking dye (technetium) doesn’t show up anywhere.