Does testosterone therapy make men more likely to die from cancer or heart problems?
Testosterone replacement therapy is not associated with increased prostate cancer incidence, prostate cancer-specific, or cardiovascular disease-specific mortality in Finnish men
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
TRT users had a 48% lower risk of dying from prostate cancer despite having similar incidence rates.
It’s counterintuitive: more men on TRT didn’t get more cancer, but those who did were far less likely to die. This suggests TRT might improve survival — or that users are healthier overall.
Practical Takeaways
Men considering TRT for low testosterone symptoms can be reassured this large study found no increased prostate cancer risk and possible survival benefits.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
TRT users had a 48% lower risk of dying from prostate cancer despite having similar incidence rates.
It’s counterintuitive: more men on TRT didn’t get more cancer, but those who did were far less likely to die. This suggests TRT might improve survival — or that users are healthier overall.
Practical Takeaways
Men considering TRT for low testosterone symptoms can be reassured this large study found no increased prostate cancer risk and possible survival benefits.
Publication
Journal
Acta Oncologica
Year
2023
Authors
A. Siltari, T. Murtola, Josefina Kausz, K. Talala, K. Taari, T. Tammela, Anssi Auvinen
Related Content
Claims (5)
Studies with lots of people and strict methods show that giving men testosterone at normal body levels doesn’t make them more likely to die or have serious heart problems.
Men between 55 and 67 who take testosterone therapy may be almost half as likely to die from prostate cancer as men who don’t take it, based on a long-term study.
Men between 55 and 67 who take testosterone therapy may be 13% less likely to die from heart disease than men who don’t take it, based on a long-term study tracking them for 18 years.
For men between 55 and 67, taking testosterone therapy doesn’t seem to make them more likely to die from any cause over 18 years — their risk is about the same as men who don’t take it.
For men between 55 and 67, taking testosterone therapy doesn’t seem to increase their chances of getting prostate cancer compared to men who don’t take it, based on a long-term study of nearly 3,000 men.