The Study
Modulation of Inflammatory Indices by Omega‐3 Fatty Acids Supplementation in Hemodialysis: A Clinical Trial Approach
This study tried to see if taking omega-3 pills reduces swelling in the body for people on dialysis. It found no clear change, but the study wasn't big enough to be sure. So we can't say omega-3 definitely helps or doesn't help — we just don't know for sure yet.
Analysis score
Maximum 90 for a randomized controlled trial.
Where the score came from
Scientists tested if taking omega-3 pills every day for two months would reduce inflammation in people on dialysis.
Where does this study sit?
Reviews of RCTs (Meta-analyses)
Max 100Randomized Trials
Max 90Reviews of Cohort Studies
Max 85Cohort Studies
Max 72Reviews of Case-Control Studies
Max 63Case-Control Studies
Max 58Cross-Sectional & Case Series
Max 50Expert Opinion
Max 571 / 100
Quality score
Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.
Key takeaways
Summary
Based on the study abstract and findings.
- 1The changes were not big enough to be meaningful or different from the placebo — so the pills didn't help reduce inflammation in this group.
- 2People who took omega-3 pills saw CRP go up from 9.86 to 11.46 mg/L and IL-6 from 17.84 to 81.82 pg/mL — similar to the placebo group.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Clinical and Translational Science
Year
2026
Authors
Hanieh Shafaei Kachaei, Khadijeh Abbasi Mobarakrh, Fatemeh Azaryan, Mahdie Torkaman, Seyed Ali Askarpour, A. R. Harsini, F. Fahimzad, Mahdi Mousavi Mele, Marziyeh Hoseinzadeh Liavoli, Neda Masoomi Golujeh, Sanaz Ataie Kashki, Sara Khoshdooz, Saeid Doaei, Masoud Khosravi, M. Gholamalizadeh
Related Content
Claims (2)
Taking omega-3 supplements every day for two months doesn't seem to lower markers of inflammation in people with advanced kidney disease who are on dialysis.
Taking 3 grams of omega-3 fatty acids daily for two months does not lower levels of two key markers of inflammation—C-reactive protein and interleukin-6—in adults with end-stage kidney disease who are receiving hemodialysis.
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.