Why being insulin resistant is like a broken fuel gauge

Original Title

The Expanding Pathogenic Role of Insulin Resistance in Human Disease.

Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms

Summary

Your body needs insulin to let sugar into cells, but sometimes cells stop listening. The pancreas tries to fix it by making more insulin, but if it can't keep up, sugar builds up in the blood. High insulin also messes with fat and blood pressure, raising heart disease risk.

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Surprising Findings

Insulin resistance can cause high blood pressure—not just correlate with it.

Most assume high blood pressure is caused by salt, stress, or genetics—but this study suggests insulin resistance and high insulin levels may directly trigger it, even in healthy rats fed fructose.

Practical Takeaways

Get a fasting insulin test if you’re thin but have family history of diabetes or heart disease—even if your blood sugar is normal.

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Publication

Journal

Diabetic medicine : a journal of the British Diabetic Association

Year

2014

Authors

A. Krentz, G. Hitman

6 citations
Analysis v1