View

The Study

Muscle hypertrophy and strength gains after resistance training with different volume matched loads: a systematic review and meta-analysis.

In simple terms

This study looked at lots of different experiments where people lifted weights with different amounts of weight but did the same total work. It found that lifting heavier weights makes you stronger, but doesn't make your muscles bigger than lifting lighter weights — as long as you do the same total amount of lifting. So it's like comparing how fast you get better at pushing a heavy cart vs. a light one — heavy cart wins for strength, but both give you the same muscle growth.

75%

Analysis score

75/ 85

Maximum 85 for a systematic review with meta-analysis.

Where the score came from

Reporting40
Methodology79
Publication100
Statistical77
Study type (basis of the score)
Systematic Review with Meta-Analysis
Level 2a - Systematic review of cohort studies
What’s the bottom line?

This study looked at whether lifting light weights or heavy weights makes your muscles bigger or stronger — as long as you do the same total amount of work.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Reviews of Cohort Studies
Level 2a
75

75 / 100

Quality score

Systematic reviews and meta-analyses of cohort studies. They sit above a single cohort study but below a single randomized trial, because the underlying evidence is still observational.

Can establish causation

Save studies & get personalized insights

Create a free account to save this study, track new evidence as it comes in, and get breakdowns of studies in the topics you care about.

Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes — if you want to get stronger, lift heavier.
  2. 2If you just want bigger muscles, you can use light or heavy weights — it doesn’t matter much, as long as you work hard and do enough total reps.
  3. 3Heavy weights (≥80% max) made people significantly stronger (1RM up more), but light, medium, and heavy weights all made muscles grow about the same amount.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme

Year

2022

Authors

L. Carvalho, R. Junior, Júlia Barreira, B. Schoenfeld, J. Orazem, R. Barroso

Open Access
81 citations
Analysis v5

Related Content

Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.