View

The Study

The Effects of Long Muscle Length Isometric versus Full Range of Motion Isotonic Training on Regional Quadriceps Femoris Hypertrophy in Resistance-Trained Individuals.

In simple terms

This study tried two different leg workouts on the same people and saw which one made their thigh muscles grow a little more. It’s like flipping a coin to decide which leg gets which workout — so we can guess one might be better. But we’re not super sure because we didn’t see how they made sure people didn’t know which workout they were doing.

54%

Analysis score

54/ 90

Maximum 90 for a randomized controlled trial.

Where the score came from

Reporting0
Methodology59
Publication100
Statistical54
Study type (basis of the score)
Randomized Controlled Trial
Level 1b - Individual RCT
What’s the bottom line?

People did either holding leg extensions at full stretch or doing full squats with weights for 6 weeks, and scientists measured how much their thigh muscles grew.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Randomized Trials
Level 1b
54

54 / 100

Quality score

Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.

Can establish causation

Save studies & get personalized insights

Create a free account to save this study, track new evidence as it comes in, and get breakdowns of studies in the topics you care about.

Key takeaways

Summary

Based on the study abstract and findings.

  1. 1The difference in top-thigh growth is small and uncertain — for most people, both methods are equally effective for overall thigh growth.
  2. 2Both methods made the front of the thigh grow about the same.
  3. 3Static holds might grow the top part of the thigh a bit more (82% chance), but it's not certain.
  4. 4The sides of the thigh didn't grow at all with either method.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme

Year

2025

Authors

Dorian Varović, Kristian Žganjer, Milo Wolf, P. Androulakis-Korakakis, B. Schoenfeld, Pavle Mikulic

2 citations
Analysis v5

Related Content

Claims (9)

Assertion

For people who are already trained, lifting weights with muscles stretched out does not result in more muscle growth than lifting with muscles shortened, and it does not result in less muscle growth than lifting through a full range of motion.

Descriptive
Read analysis
Assertion

When training volume and intensity are the same, lifting weights with greater resistance at longer muscle lengths results in the same amount of muscle growth as lifting with greater resistance at shorter muscle lengths.

Comparative
Read analysis
Assertion

Doing static leg exercises with your thigh muscles fully stretched might grow the upper part of your thigh more than doing regular leg exercises that move through a full range, but both types of exercise end up making your whole quadriceps muscle about the same size.

Causal
Read analysis
Assertion

If you train your quads using either holding a static position with your legs stretched out or doing full squat-like movements, both ways build your thigh muscles about the same amount — neither one is better than the other.

Descriptive
Read analysis
Assertion

If you're already someone who lifts weights, doing either static holds with your muscles stretched out or full-range weight exercises won't make the outer part of your thigh noticeably bigger in just six weeks.

Descriptive
Read analysis
Assertion

In people who regularly lift weights, training with static muscle contractions at stretched muscle positions and training with full-range dynamic movements produce similar increases in quadriceps muscle size over six weeks, though static training leads to slightly more growth in the upper part of the front thigh.

Descriptive
Read analysis
Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.