The Study
The Effects of Long Muscle Length Isometric versus Full Range of Motion Isotonic Training on Regional Quadriceps Femoris Hypertrophy in Resistance-Trained Individuals.
This study tried two different leg workouts on the same people and saw which one made their thigh muscles grow a little more. It’s like flipping a coin to decide which leg gets which workout — so we can guess one might be better. But we’re not super sure because we didn’t see how they made sure people didn’t know which workout they were doing.
Analysis score
Maximum 90 for a randomized controlled trial.
Where the score came from
People did either holding leg extensions at full stretch or doing full squats with weights for 6 weeks, and scientists measured how much their thigh muscles grew.
Where does this study sit?
Reviews of RCTs (Meta-analyses)
Max 100Randomized Trials
Max 90Reviews of Cohort Studies
Max 85Cohort Studies
Max 72Reviews of Case-Control Studies
Max 63Case-Control Studies
Max 58Cross-Sectional & Case Series
Max 50Expert Opinion
Max 554 / 100
Quality score
Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.
Key takeaways
Summary
Based on the study abstract and findings.
- 1The difference in top-thigh growth is small and uncertain — for most people, both methods are equally effective for overall thigh growth.
- 2Both methods made the front of the thigh grow about the same.
- 3Static holds might grow the top part of the thigh a bit more (82% chance), but it's not certain.
- 4The sides of the thigh didn't grow at all with either method.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
Year
2025
Authors
Dorian Varović, Kristian Žganjer, Milo Wolf, P. Androulakis-Korakakis, B. Schoenfeld, Pavle Mikulic
Related Content
Claims (9)
For people who are already trained, lifting weights with muscles stretched out does not result in more muscle growth than lifting with muscles shortened, and it does not result in less muscle growth than lifting through a full range of motion.
When training volume and intensity are the same, lifting weights with greater resistance at longer muscle lengths results in the same amount of muscle growth as lifting with greater resistance at shorter muscle lengths.
Doing static leg exercises with your thigh muscles fully stretched might grow the upper part of your thigh more than doing regular leg exercises that move through a full range, but both types of exercise end up making your whole quadriceps muscle about the same size.
If you train your quads using either holding a static position with your legs stretched out or doing full squat-like movements, both ways build your thigh muscles about the same amount — neither one is better than the other.
If you're already someone who lifts weights, doing either static holds with your muscles stretched out or full-range weight exercises won't make the outer part of your thigh noticeably bigger in just six weeks.
In people who regularly lift weights, training with static muscle contractions at stretched muscle positions and training with full-range dynamic movements produce similar increases in quadriceps muscle size over six weeks, though static training leads to slightly more growth in the upper part of the front thigh.
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.