How some body molecules wake up an immune alarm

Original Title

Poly (I:C) and hyaluronic acid directly interact with NLRP3, resulting in the assembly of NLRP3 and ASC in a cell-free system

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Summary

Scientists found that two natural molecules—poly(I:C) and hyaluronic acid—can directly touch a protein called NLRP3 and make it team up with other proteins to turn on an inflammation signal.

Proposed Mechanism

No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.

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