Do statins calm angry arteries?
Effect of statins on arterial wall inflammation as assessed by 18F-FDG PET CT: an updated systematic review and meta-analysis
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Statins don't just lower cholesterol—they also quiet down inflammation in artery walls, which can prevent heart attacks.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 547 / 100
Evidence Score
The highest quality evidence. These studies systematically search, appraise, and synthesize results from multiple individual studies, providing the most reliable summary of current knowledge.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Statins don't just lower cholesterol—they also quiet down inflammation in artery walls, which can prevent heart attacks.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 547 / 100
Evidence Score
The highest quality evidence. These studies systematically search, appraise, and synthesize results from multiple individual studies, providing the most reliable summary of current knowledge.
Publication
Authors
Jamialahmadi T, Reiner Ž, Simental-Mendia LE, Almahmeed W, Karav S, Eid AH, Giammarile F, Sahebkar A
Related Content
Claims (6)
Statins reduce intraplaque inflammation, thereby decreasing the likelihood of atherosclerotic plaque rupture and subsequent thrombotic events.
Taking statins may help calm down inflammation in the walls of arteries, which can be seen on a special scan that tracks sugar use by inflamed cells.
A special scan that tracks sugar use in artery walls can reliably show whether inflammation is going down — and it works in different parts of the body’s arteries.
Stronger statins seem to calm artery inflammation better than weaker ones, based on scans that show how much sugar inflamed cells are using.
When statins lower bad cholesterol, artery inflammation tends to go down too — the two seem to move together.