The Study
Muscle Growth Is Very Strongly Correlated with Strength Gains after Lower Body Resistance Training: New Insight from Within-Participant Associations
This study found that when guys got stronger from lifting weights, their muscles also got bigger — and the bigger the muscle growth, the stronger they got. But it doesn’t prove that bigger muscles made them stronger — maybe something else did, like how their brain told their muscles to work harder.
Analysis score
Maximum 90 for a randomized controlled trial.
Where the score came from
When you lift weights, your muscles grow bigger—and that’s the main reason you get stronger, not just your nerves firing better.
Where does this study sit?
Reviews of RCTs (Meta-analyses)
Max 100Randomized Trials
Max 90Reviews of Cohort Studies
Max 85Cohort Studies
Max 72Reviews of Case-Control Studies
Max 63Case-Control Studies
Max 58Cross-Sectional & Case Series
Max 50Expert Opinion
Max 567 / 100
Quality score
Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.
Key takeaways
Summary
Based on the study abstract and findings.
- 1Yes—this means if you want to get stronger, building bigger muscles matters way more than just learning to use them better.
- 2Muscles grew 12.7% bigger; strength went up a lot.
- 3Muscle growth explained over 85% of strength gains; nerves explained less than 15%.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Medicine and Science in Sports and Exercise
Year
2025
Authors
E. Marques, T. G. Balshaw, M. Funnell, Emmet J. McDermott, S. Maeo, Lewis J. James, Jonathan P Folland
Related Content
Claims (10)
In healthy young men who had not previously trained, 15 weeks of leg resistance training was associated with a strong relationship between increases in quadriceps muscle size and increases in knee extension strength.
When guys who’ve never lifted weights before train their legs for 15 weeks, the more their muscles grow, the stronger they get—so muscle growth is mostly why they get stronger.
In healthy young men who have not previously trained, greater electrical activity in the quadriceps muscle during maximum effort is linked to larger increases in knee extension strength after 15 weeks of resistance training.
When guys who’ve never lifted weights before start training, the more their thigh muscles ‘fire up’ during max efforts, the stronger they tend to get—both in holding a heavy position and in lifting one heavy weight.
When guys who’ve never lifted weights start training, most of their strength gains come from their muscles getting bigger—not from their brain and nerves getting better at telling muscles to work harder.
When scientists look at how one person changes over time—like how their muscles grow and get stronger together—they find a super strong link. But when they compare different people to each other, that link looks much weaker.
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.