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The Study

Muscle Growth Is Very Strongly Correlated with Strength Gains after Lower Body Resistance Training: New Insight from Within-Participant Associations

In simple terms

This study found that when guys got stronger from lifting weights, their muscles also got bigger — and the bigger the muscle growth, the stronger they got. But it doesn’t prove that bigger muscles made them stronger — maybe something else did, like how their brain told their muscles to work harder.

67%

Analysis score

67/ 90

Maximum 90 for a randomized controlled trial.

Where the score came from

Reporting0
Methodology79
Publication100
Statistical77
Study type (basis of the score)
Randomized Controlled Trial
Level 2b - Individual cohort study
What’s the bottom line?

When you lift weights, your muscles grow bigger—and that’s the main reason you get stronger, not just your nerves firing better.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Cohort Studies
Level 2b
67

67 / 100

Quality score

Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.

Cannot establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes—this means if you want to get stronger, building bigger muscles matters way more than just learning to use them better.
  2. 2Muscles grew 12.7% bigger; strength went up a lot.
  3. 3Muscle growth explained over 85% of strength gains; nerves explained less than 15%.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

Medicine and Science in Sports and Exercise

Year

2025

Authors

E. Marques, T. G. Balshaw, M. Funnell, Emmet J. McDermott, S. Maeo, Lewis J. James, Jonathan P Folland

Open Access
3 citations
Analysis v5

Related Content

Claims (10)

Assertion

In healthy young men who had not previously trained, 15 weeks of leg resistance training was associated with a strong relationship between increases in quadriceps muscle size and increases in knee extension strength.

Correlational
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Assertion

When guys who’ve never lifted weights before train their legs for 15 weeks, the more their muscles grow, the stronger they get—so muscle growth is mostly why they get stronger.

Correlational
Read analysis
Assertion

In healthy young men who have not previously trained, greater electrical activity in the quadriceps muscle during maximum effort is linked to larger increases in knee extension strength after 15 weeks of resistance training.

Correlational
Read analysis
Assertion

When guys who’ve never lifted weights before start training, the more their thigh muscles ‘fire up’ during max efforts, the stronger they tend to get—both in holding a heavy position and in lifting one heavy weight.

Correlational
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Assertion

When guys who’ve never lifted weights start training, most of their strength gains come from their muscles getting bigger—not from their brain and nerves getting better at telling muscles to work harder.

Quantitative
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Assertion

When scientists look at how one person changes over time—like how their muscles grow and get stronger together—they find a super strong link. But when they compare different people to each other, that link looks much weaker.

Correlational
Read analysis
Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.