The Study
The possibilities of correction of premature greying of hair and involutive hair changes
This study is like a teacher reading aloud from a bunch of old science books and saying, 'Some people think this causes hair to turn gray, and some people think this cream might help.' But they didn’t do any experiments themselves, so we can’t say for sure if any of it’s true.
Analysis score
Maximum 5 for a narrative review.
Where the score came from
Hair turns gray early for different reasons depending on your background, and it's often because of stress, genes, or not enough vitamins. Scientists think a chemical imbalance in the hair follicle causes it, and there's a special molecule and body system that might help bring back color or grow hair better.
Where does this study sit?
Systematic Reviews & Meta-analyses
Max 100Randomized Trials
Max 90Cohort Studies
Max 72Case-Control
Max 58Cross-Sectional
Max 44Case Reports & Series
Max 30Expert Opinion
Max 51 / 100
Quality score
Based on clinical experience or non-systematic literature reviews. The lowest level of evidence as they are most susceptible to bias and personal perspective.
Key takeaways
Summary
Based on the study abstract and findings.
- 1The results suggest that for some people, fixing a vitamin deficiency might help hair color return, but it doesn't always work.
- 2Other treatments are still being studied.
- 3Hair turns gray before age 20 in Caucasians, 25 in Asians, 30 in Africans.
- 4B12 deficiency may rarely reverse gray hair.
- 5Palmitoyl tetrapeptide-20 is used to restore pigment.
- 6Endocannabinoid system is a possible target for hair growth.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Medical alphabet
Year
2024
Authors
E. A. Shatokhina, A. V. Topskaya, L. S. Kruglova
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.