Can a protein boost and sprinting help you eat less?
Acute L-Leucine Supplementation and Sprint Exercise Elicit Distinct Appetite and Inflammatory Responses in Persons with Overweight: A Randomized, Counterbalanced, and Crossover Design Study
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists tested if taking a protein powder (leucine) and doing short, intense bike sprints could make overweight men feel less hungry and eat less.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 574 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists tested if taking a protein powder (leucine) and doing short, intense bike sprints could make overweight men feel less hungry and eat less.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 574 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Publication
Authors
França E, Thomatieli-Santos RV, Aquino RC, Cavalcante MM, Salvalágio BR, Hofmann P, Martins RA, Baptista LC, Lira FS, Caperuto EDC
Related Content
Claims (5)
In sedentary overweight adult men, one session of high-intensity sprinting reduces how hungry they feel and how much food they eat on the same day, regardless of whether they take L-leucine.
Taking L-leucine supplements at a dose of 70 mg per kilogram of body weight three times a day lowers how hungry sedentary overweight men feel, but does not change how full they feel or how much they eat.
In overweight men, taking L-leucine supplements along with sprinting increases levels of IL-6 and IL-1β, which reduces the anti-inflammatory effect seen when sprinting is done without the supplement.
In overweight men, higher levels of the inflammatory marker IL-6 above 4 pg/mL are linked to lower self-reported hunger, and higher levels of the hormone PYY above 67.89 pg/mL are linked to an even greater reduction in hunger.
Consuming 2 grams of leucine with a low-protein meal reduces hunger compared to not taking leucine, and increasing the dose up to 2 grams increases this reduction in hunger.