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The Study

Demographic Characteristics and Association of Serum Vitamin B12, Ferritin and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases

In simple terms

This study found that kids with gray hair early often had low B12 or thyroid problems — but it didn’t prove those problems made the hair turn gray. It just saw that they happened together, like noticing that kids who eat a lot of candy also have more cavities — but candy might not be the cause.

28%

Analysis score

28/ 58

Maximum 58 for a case-control study.

Where the score came from

Reporting0
Methodology7
Publication100
Statistical23
Study type (basis of the score)
Case-Control Study
Level 3b - Individual case-control study
What’s the bottom line?

Some kids in India start getting gray hair as young as 5 years old. This study looked at why that happens.

Where does this study sit?

Systematic Reviews & Meta-analyses

Max 100

Randomized Trials

Max 90

Cohort Studies

Max 72

Case-Control

Max 58

Cross-Sectional

Max 44

Case Reports & Series

Max 30

Expert Opinion

Max 5
StrongerWeaker
Cross-Sectional
Level 3b
28

28 / 100

Quality score

A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.

Cannot establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes — early graying in kids is often genetic and linked to low B12 or thyroid issues, not iron deficiency.
  2. 290% of kids had a family member with early gray hair.
  3. 31 in 8 had low vitamin B12.
  4. 41 in 4 had underactive thyroid.
  5. 5Iron levels were normal.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

Indian Journal of Dermatology

Year

2017

Authors

S. Sonthalia, A. Priya, D. Tobin

Open Access
44 citations
Analysis v3
Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.