More Sets Make You Stronger and Bigger — But Only Up to a Point

Original Title

The Resistance Training Dose-Response: Meta-Regressions Exploring the Effects of Weekly Volume and Frequency on Muscle Hypertrophy and Strength Gain

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Summary

Doing more resistance training sets each week makes your muscles bigger and stronger, but after a certain amount, you get less extra benefit. Doing workouts more often helps you get stronger, but doesn’t necessarily make your muscles bigger if you’re already doing enough total sets.

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Surprising Findings

Training frequency doesn’t reliably increase muscle size when total volume is held constant.

For decades, fitness culture preached that training each muscle 2–3x/week was optimal for growth—this study says if you do the same total sets, spreading them out doesn’t help size.

Practical Takeaways

If your goal is muscle growth, focus on hitting 10–20 direct sets per muscle group per week—don’t stress about splitting them across 2 or 5 days.

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Moderate QualityOverall Score

Publication

Authors

Joshua Pelland, Jacob Remmert, Zac Robinson, Seth Hinson, Michael Zourdos

Open Access
Analysis v1